Seminar

MWRI Work-in-Progress Seminar: "The potential of broadly neutralizing anti-HIV-1 antibodies to function as dual-compartment topical microbicides"



Date
November 5, 2013
Time
12:00 PM - 1:00 PM
Speaker(s)
Yanille Scott, BS
Student Researcher, Magee-Womens Research Institute, University of Pittsburgh, Graduate School of Public Health
Location
Magee-Womens Research Institute, 204 Craft Ave, Conf Center, 1st Floor
Contact
Kelli
Program Coordinator


412-641-6052
klazar@mwri.magee.edu
Admission
Physicians earn 1 CME credit
Registration is not required, light lunch provided
Description

In this presentation I will provide a broad overview of the different classes of HIV microbicides used in the past; and discuss the potential of broadly neutralizing monoclonal anti-HIV antibodies to function as effective anti-HIV microbicides. I will present preliminary evaluations of nAb efficacy in preventing cell-free HIV transmission in an human ex vivo mucosal model and discuss their capacity to prevent cell-associated transmission.