Research Seminar

MWRI WIP: Loss of Prdx1 function promotes synthetic lethality in response to DNA-damage



Date
May 6, 2014
Time
12:00 PM - 1:00 PM
Speaker(s)
Myriam Attar
Postdoctoral Fellow, UPCI, Magee-Womens Research Institute
Location
Magee-Womens Research Institute, Conf Center, 204 Craft Ave
Admission
Physicians earn 1.0 CME credits
Light lunch provided and registration is not required.
Description

Peroxiredoxin 1 (Prdx1) is is a ubiquitously expressed and highly conserved member of a family of antioxidant proteins. Prdx1 is believed to protect macromolecules from ROS damage beyond its enzymatic activity of scavenging H2O2. We explore the role of this enzyme in DNA damage.