MWRI Work-in-Progress “Matching Extrinsic Conditions to Bioenergetics: Novel Strategies to Enhance the In Vitro Maintenance of Mammalian Spermatogonial Stem Cells”

March 10, 2015
12:00 PM - 1:00 PM
Jon Oatley, PhD
Director, Center for Reproductive Biology, School of Molecular Biosciences
Magee-Womens Research Institute, 204 Craft Ave, Conf Center
Physicians earn 1.0 CME credits
Light lunch provided. Registration not required.

1. Define the functional and molecular features of a male germline stem cell.
2. Discuss the importance of male germline stem cell culture and limitations of current methodology.
3. Introduce the concept that stem cells and progenitors possess unique bioenergetics.
4. Demonstrate that matching the extrinsic environment to the bioenergetics of stem cells enhances maintenance of the population in vitro.