MWRI Work-in-Progress "Feasting, Fasting and Fermenting: using yeast as a model for glucose stress signaling."

October 27, 2015
12:00 PM - 1:00 PM
Martin Schmidt, PhD
Associate Professor of Microbiology and Molecular GeneticsUniversity of Pittsburgh School of Medicine,
Magee-Womens Research Institute, 204 Craft Ave, Conf Center 1st Floor
Physicians earn 1.0 CMEs
Light lunch provided. Registration is not required.
The AMP-activated protein kinase is metabolic sensor in all eukaryotic cells. Studies of this signaling pathway in mammalian cells and model systems have combined to reveal a conserved mechanism for sensing and responding to changes in nutrient availability. Our studies in yeast have identified new components in this pathway and have uncovered distinct functions of the different AMPK isoforms.