University of Pittsburgh researchers discovered that lysosomal dysfunction, driven by a genetic variant affecting the NCOA7 protein, contributes to inflammation and increased mortality risk in pulmonary arterial hypertension—revealing potential biomarkers and therapeutic targets.

Using tools like brain imaging, RNA sequencing and microbiome analysis, University of Pittsburgh medical and dental researchers are leading a study to better understand and treat a group of painful jaw disorders.

Four major centers within the University of Pittsburgh School of Medicine, which each approach pain research from a different angle, have now joined forces under the new Pittsburgh Pain Consortium.