Biomarker tests detect early Alzheimer’s pathology.

Various teams at the University of Pittsburgh Health Sciences are going beyond decreasing opioid prescribing and are identifying and using evidence-based ideas to make a real difference in addressing the crisis.

Despite enthusiasm around the potential benefits of the drug sotatercept for patients with pulmonary hypertension, Pitt experts and colleagues observed a significant rate of new or worsening pericardial effusions in PAH patients treated with it.

University of Pittsburgh researchers discovered that lysosomal dysfunction, driven by a genetic variant affecting the NCOA7 protein, contributes to inflammation and increased mortality risk in pulmonary arterial hypertension—revealing potential biomarkers and therapeutic targets.

A doctor flips the framework for diagnosing inflammatory and autoimmune genetic disorders.